This is just the "bookmarking" blog where I will post only links and perhaps abstracts I've come across that are of interest to me and may someday be discussed in a blog post.

See something you're interested in discussing? Shoot me an email!


Wednesday, December 21, 2011

Effects of fatty acid regulation on visfatin gene expression in adipocytes

Effects of fatty acid regulation on visfatin gene expression in adipocytes

Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics

Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics

Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs obese type 2 diabetes

Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs obese type 2 diabetes

Acute injection of ASP in the third ventricle inhibits food intake and locomotor activity in rats

Acute injection of ASP in the third ventricle inhibits food intake and locomotor activity in rats

C5L2 Is a Functional Receptor for Acylation-stimulating Protein

C5L2 Is a Functional Receptor for Acylation-stimulating Protein

The effects of acylation stimulating protein supplementation VS antibody neutralization on energy expenditure in wildtype mice

The effects of acylation stimulating protein supplementation VS antibody neutralization on energy expenditure in wildtype mice

Acylation-stimulating protein/C5L2-neutralizing antibodies alter triglyceride metabolism in vitro and in vivo

Acylation-stimulating protein/C5L2-neutralizing antibodies alter triglyceride metabolism in vitro and in vivo

FOREARM METABOLISM IN OBESITY AND ITS RESPONSE TO INTRAARTERIAL INSULIN. CHARACTERIZATION OF INSULIN RESISTANCE AND EVIDENCE FOR ADAPTIVE

FOREARM METABOLISM IN OBESITY AND ITS RESPONSE TO INTRA-ARTERIAL INSULIN. CHARACTERIZATION OF INSULIN RESISTANCE AND EVIDENCE FOR ADAPTIVE HYPERINSULINISM

Monday, December 19, 2011

Effect of Ethanol on Ketone Metabolism

Effect of Ethanol on Ketone Metabolism

Insulin Regulates Testosterone and Sex Hormone-Binding Globulin Concentrations in Adult Normal Weight and Obese Men

Insulin Regulates Testosterone and Sex Hormone-Binding Globulin Concentrations in Adult Normal Weight and Obese Men

Effect of a high-protein, very-low-calorie diet on resting metabolism, thyroid hormones, and energy expenditure of obese middle-aged women

Effect of a high-protein, very-low-calorie diet on resting metabolism, thyroid hormones, and energy expenditure of obese middle-aged women

On the mechanism of diazoxide-induced hyperglycemia

On the mechanism of diazoxide-induced hyperglycemia

Liver-Specific igf-1 Gene Deletion Leads to Muscle Insulin Insensitivity

Liver-Specific igf-1 Gene Deletion Leads to Muscle Insulin Insensitivity

Sunday, December 18, 2011

Starvation Diabetes

Starvation Diabetes

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine

Efficacy and Safety of Troglitazone in the Treatment of Lipodystrophy Syndromes

Efficacy and Safety of Troglitazone in the Treatment of Lipodystrophy Syndromes

Comparison of energy metabolism in Insulin-Dependent and Non-Insulin-Dependent diabetes mellitus

Comparison of energy metabolism in Insulin-Dependent and Non-Insulin-Dependent diabetes mellitus

Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism

Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism

Tuesday, December 13, 2011

De Novo Lipogenesis and Stearoyl-CoA Desaturase Are Coordinately Regulated in the Human Adipocyte and Protect against Palmitate-induced Cell Injury

De Novo Lipogenesis and Stearoyl-CoA Desaturase Are Coordinately Regulated in the Human Adipocyte and Protect against Palmitate-induced Cell Injury

Keith Frayn's group   (hat tip Beth@WM)

Arguments In Favor Of Ketogenic Diets

Arguments In Favor Of Ketogenic Diets

Complications of the Ketogenic Diet

Complications of the Ketogenic Diet

Effect of a low fat versus a low carbohydrate weight loss dietary intervention on biomarkers of long term survival in breast cancer patients ('CHOICE'): study protocol

Effect of a low fat versus a low carbohydrate weight loss dietary intervention on biomarkers of long term survival in breast cancer patients ('CHOICE'): study protocol

Entrainment of the Diurnal Rhythm of Plasma Leptin to Meal Timing

Entrainment of the Diurnal Rhythm of Plasma Leptin to Meal Timing

Effects at Two Years of a Low-Fat, High-Carbohydrate Diet on Radiologic Features of the Breast: Results From a Randomized Trial

Effects at Two Years of a Low-Fat, High-Carbohydrate Diet on Radiologic Features of the Breast: Results From a Randomized Trial

Results: After 2 years, the total area of the breast was reduced by an average of 233.7 mm2 (2.4%) (95% confidence interval [CI] = 106.9−360.6) in the intervention group compared with an average increase of 26.3 mm2 (0.3%) (95% CI = −108.0160.5) in the control group (P = .01). The area of density was reduced by 374.4 mm2 (6.1%) (95% CI = 235.1−513.8) in the intervention group compared with an average of 127.7 mm2 (2.1%) (95% CI = 8.6−246.7) in the control group (P = .01). Weight loss was associated with a reduction in breast area. The effect of the intervention on breast area was only marginally statistically significant after weight change, menopausal status, and age at trial entry were taken into account (P = .06). Greater weight loss and becoming postmenopausal were associated with statistically significant reductions in the area of density on the mammographic image at 2 years (P = .04 and P<.001, respectively).

Macronutrient Intake and Change in Mammographic Density at Menopause: Results from a Randomized Trial

Macronutrient Intake and Change in Mammographic Density at Menopause: Results from a Randomized Trial

Reduction in total or saturated fat intake or cholesterol intake was significantly associated with decreased dense area (p ≤ .004). The most significant dietary variable associated with reduction in percentage of density was reduction in dietary cholesterol intake (P = 0.001), although reducing saturated fat intake was of borderline significance (P = 0.05).

Saturday, December 3, 2011

Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier

Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier

The Brain-Gut-Islet Connection

The Brain-Gut-Islet Connection

(cited by Todd Becker in his HH post)

An Oral Lipid Challenge and Acute Intake of Caffeinated Coffee Additively Decrease Glucose Tolerance in Healthy Men

An Oral Lipid Challenge and Acute Intake of Caffeinated Coffee Additively Decrease Glucose Tolerance in Healthy Men

Incretins decrease??

Incretin Secretion in Relation to Meal Size and Body Weight in Healthy Subjects and People with Type 1 and Type 2 Diabetes Mellitus

Incretin Secretion in Relation to Meal Size and Body Weight in Healthy Subjects and People with Type 1 and Type 2 Diabetes Mellitus

Difference in leptin response to a high-fat meal between lean and obese men

Difference in leptin response to a high-fat meal between lean and obese men

Effect of Fasting, Refeeding, and Dietary Fat Restriction on Plasma Leptin Levels

Effect of Fasting, Refeeding, and Dietary Fat Restriction on Plasma Leptin Levels

Postprandial Leptin Response to Carbohydrate and Fat Meals in Obese Women

Postprandial Leptin Response to Carbohydrate and Fat Meals in Obese Women

Wednesday, November 30, 2011

Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women

Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women

High protein intake sustains weight maintenance after body weight loss in humans

High protein intake sustains weight maintenance after body weight loss in humans

Impaired Actions of Insulin-like Growth Factor 1 on Protein Synthesis and Degradation in Skeletal Muscle of Rats with Chronic Renal Failure

High Glycemic Index Carbohydrate Diet Alters the Diurnal Rhythm of Leptin But Not Insulin Concentrations

High Glycemic Index Carbohydrate Diet Alters the Diurnal Rhythm of Leptin But Not Insulin Concentrations

Monday, November 21, 2011

Is Carb Content of HFCS Underestimated?

Carbohydrate Analysis of High Fructose Corn Syrup (HFCS) Containing Commercial Beverages

The carbohydrate analysis of HFCS is based on methods which first hydrolyze the syrup into simple sugars before quantitative analysis. We have examined whether HFCS can be hydrolyzed under the same conditions suitable for hydrolyzing sucrose. A new GC/MS method for the quantitation of fructose and glucose as their methoxyamine derivatives and 13C labeled recovery standards was used to determine the carbohydrate content of HFCS in 10 commercial beverages. Samples were analyzed before and after acid hydrolysis. The carbohydrate contents in commercial beverages determined without acid hydrolysis were in agreement with the carbohydrate contents provided on the food labels. However, the carbohydrate contents of beverages determined after acid hydrolysis were substantially (4–5 fold) higher than the listed values of carbohydrates. As fructose and glucose in HFCS may exist as monosaccharides, disaccharides and/or oligosaccharides, analysis of the carbohydrate content of HFCS containing samples may yield widely different results depending on the degree of hydrolysis of the oligosaccharides. With inclusion of mild acid hydrolysis, all samples showed significantly higher fructose and glucose content than the listed values of carbohydrates on the nutrition labels. The underestimation of carbohydrate content in beverages may be a contributing factor in the development of obesity in children.

Monday, June 6, 2011

A collection of links to IGF-1, gut permeability, gut flora and T2 Diabetes

Health-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketones  (abstract only)


IGF-1 and gut permeability:

http://www.ncbi.nlm.nih.gov/pubmed/18716194
http://www.ncbi.nlm.nih.gov/pubmed/18223378
http://www.ncbi.nlm.nih.gov/pubmed/16434425
http://www.ncbi.nlm.nih.gov/pubmed/11484917
http://www.ncbi.nlm.nih.gov/pubmed/8418780

Colostrum and gut permeability:

http://www.ncbi.nlm.nih.gov/pubmed/21148400
http://www.ncbi.nlm.nih.gov/pubmed/15919136
http://www.ncbi.nlm.nih.gov/pubmed/15734716
http://www.ncbi.nlm.nih.gov/pubmed/14527963
http://www.ncbi.nlm.nih.gov/pubmed/11352778

Colostrum and healthy gut microbiota:

http://www.ncbi.nlm.nih.gov/pubmed/18641188

Diabetes type 2 and gut permeabitily/microbiota:

http://www.ncbi.nlm.nih.gov/pubmed/21382153
http://www.ncbi.nlm.nih.gov/pubmed/20804522
http://www.ncbi.nlm.nih.gov/pubmed/20876708
http://www.ncbi.nlm.nih.gov/pubmed/18178333

Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1

Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1

Aging and Longevity The IGF-1 Enigma

Aging and Longevity The IGF-1 Enigma

Sunday, May 22, 2011

Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol

Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol  (abstract only) 

Chylomicron metabolism

Chylomicron metabolism  (several animal species)

High postprandial triglyceridemia in patients with type 2 diabetes and microalbuminuria

High postprandial triglyceridemia in patients with type 2 diabetes and microalbuminuria

Postprandial lipemia: An under-recognized atherogenic factor in patients with diabetes mellitus

Postprandial lipemia: An under-recognized atherogenic factor in patients with diabetes mellitus
(abstract only)

Effects of lipoproteins on plasma viscosity

Effects of lipoproteins on plasma viscosity   (abstract only)

Tuesday, April 12, 2011

Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance

Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance

Fat cell enlargement is an independent marker of insulin resistance and ‘hyperleptinaemia'

Fat cell enlargement is an independent marker of insulin resistance and ‘hyperleptinaemia'

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1 H NMR spectroscopy study

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study

Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

(Frayn)

Plasma NEFA Storage in Adipose Tissue in the Postprandial State: Sex and Regional Differences

Plasma NEFA Storage in Adipose Tissue in the Postprandial State: Sex and Regional Differences

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse

Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse

Monday, April 4, 2011

Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids

Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids

A Synopsis of Research in Cardiac Apoptosis and Its Application to Congestive Heart Failure

A Synopsis of Research in Cardiac Apoptosis and Its Application to Congestive Heart Failure

Saturated, but Not Unsaturated, Fatty Acids Induce Apoptosis of Human Coronary Artery Endothelial Cells via Nuclear Factor-κB Activation

Saturated, but Not Unsaturated, Fatty Acids Induce Apoptosis of Human Coronary Artery Endothelial Cells via Nuclear Factor-κB Activation

The effect of dietary carbohydrate:fat ratio on energy intake by adult women

The effect of dietary carbohydrate:fat ratio on energy intake by adult women

Energy intake required to maintain body weight is not affected by wide variation in diet composition.

Energy intake required to maintain body weight is not affected by wide variation in diet composition.

Monday, February 28, 2011

Glucagon-like peptide-1 prevents beta cell glucolipotoxicity

Glucagon-like peptide-1 prevents beta cell glucolipotoxicity

Mechanism of insulin-stimulated clearance of plasma nonesterified fatty acids in humans

Mechanism of insulin-stimulated clearance of plasma nonesterified fatty acids in humans

Relationship between Total and High Molecular Weight Adiponectin Levels and Plasma Nonesterified Fatty Acid Tolerance during Enhanced Intravascular Triacylglycerol Lipolysis in Men

Relationship between Total and High Molecular Weight Adiponectin Levels and Plasma Nonesterified Fatty Acid Tolerance during Enhanced Intravascular Triacylglycerol Lipolysis in Men

On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans

On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans

Increased Postprandial Nonesterified Fatty Acid Appearance and Oxidation in Type 2 Diabetes Is Not Fully Established in Offspring of Diabetic Subjects

Increased Postprandial Nonesterified Fatty Acid Appearance and Oxidation in Type 2 Diabetes Is Not Fully Established in Offspring of Diabetic Subjects

Fatty Acid Signaling in the β-Cell and Insulin Secretion

Fatty Acid Signaling in the β-Cell and Insulin Secretion

Life and death decisions of the pancreatic b-cell: the role of fatty acids

Life and death decisions of the pancreatic b-cell: the role of fatty acids

Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-kappaB activation

Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-kappaB activation

B cell Adaptation and Decompensation during the Progression of Diabetes

B cell Adaptation and Decompensation during the Progression of Diabetes